Golden Retriever Lifetime Study: Whole genome genotyping of Golden Retrievers on Axiom HD Arrays

Description

Morris Animal Foundation’s Golden Retriever Lifetime Study is a longitudinal, prospective study following 3044 golden retrievers. The Study’s purpose is to identify the nutritional, environmental, lifestyle and genetic risk factors for cancer and other diseases. The Golden Oldie’s study enrolled an additional cohort of golden retrievers that had reached the age of 12 years or older and had not yet been diagnosed with a malignant cancer. This population can be used as a control group for conditions with high mortality in younger age. This dataset contains the data for ~1.1 million genetic markers from 3224 unique individual dogs processed using Axiom Canine Genotyping Array Sets A and B. Of the 3244 individual samples, 3024 were from the Golden Retriever Lifetime Study cohort and 200 from the Golden Oldies cohort.

Update Frequency

Static

License

CC-BY-SA

Documentation

https://datacommons.morrisanimalfoundation.org/artisanal_dataset/151

Managed By

Morris Animal Foundation

See all datasets managed by Morris Animal Foundation.

Contact

gknaddison@morrisanimalfoundation.org

How to Cite

Golden Retriever Lifetime Study: Whole genome genotyping of Golden Retrievers on Axiom HD Arrays was accessed on DATE from https://registry.opendata.aws/maf-genome.

Usage Examples

Tutorials

• GRLS GWAS Tutorial by Tamer Mansour
  

Publications

• Cohort profile: The Golden Retriever Lifetime Study (GRLS) by Michael K. Guy, Rodney L. Page, Wayne A. Jensen, Patricia N. Olson, J. David Haworth, Erin E. Searfoss, and Diane E. Brown
  
• The Golden Retriever Lifetime Study: establishing an observational cohort study with translational relevance for human health by Julia Labadie, Brenna Swafford, Mara DePena, Kathy Tietje, Rodney Page, Janet Patterson-Kane